Prescription weight loss from a name you can trust
Compounded semaglutide or tirzepatide, prescribed online by a licensed U.S. provider and shipped from a licensed U.S. pharmacy. One honest price at every dose. No insurance needed.
- A licensed U.S. provider reviews every visit
- Same price at every dose, nothing hidden
- Only billed if prescribed
Monthly plans from $175. 12-month plans from $99/mo. Plans never auto-renew.
- LegitScript certified
- Licensed U.S. providers
- U.S. company, Texas
- No insurance needed
- Plans never auto-renew
Two GLP-1 options. One honest price.
Both are once-weekly injections with the provider visit, supplies and cold shipping built in. Your price stays the same as your dose goes up.
Compounded · GLP-1
Semaglutide
A once-weekly GLP-1 receptor agonist, prescribed by a licensed U.S. provider. Our lowest-priced option.
From$99/month
*12-month plan, $1,188 one payment. Monthly plan $175.
- Once-weekly injection
- Acts on the GLP-1 receptor
- Same price at every dose
- Provider visit, supplies and shipping included
Prescription required. A licensed provider decides whether semaglutide is right for you, and you are only billed if they prescribe it. Compounded semaglutide is not FDA-approved.
Compounded · GLP-1 + GIP
Tirzepatide
A once-weekly injection that acts on two hormone receptors, GLP-1 and GIP, prescribed by a licensed U.S. provider.
From$149/month
*12-month plan, $1,788 one payment. Monthly plan $285.
- Once-weekly injection
- Acts on both GLP-1 and GIP receptors
- Same price at every dose
- Provider visit, supplies and shipping included
Prescription required. A licensed provider decides whether tirzepatide is right for you, and you are only billed if they prescribe it. Compounded tirzepatide is not FDA-approved.
Not sure which one? Start with either. Your provider reviews your health history and can recommend the better fit before anything ships. Compounded medications are not FDA-approved.
Getting started with Rx.com
Three simple steps, all online. No waiting rooms and no insurance paperwork.
Take the 2-minute visit
Answer a few confidential health questions online and pick your medication.
A licensed provider reviews it
A provider licensed in your state reviews your visit, usually within 24 hours. Not prescribed? You are not billed.
Delivered to your door
A licensed U.S. pharmacy prepares your prescription and ships it cold-packed with everything you need to start.
Not a pop-up weight loss site. This is Rx.com.
A lot of GLP-1 websites appeared overnight. Before you hand anyone your health history and your card, you should know exactly who they are. Here is who we are.
LegitScript certified
Independently reviewed and certified by LegitScript, the standard Google and the card networks use to vet online pharmacies and telehealth. Verify it yourself.
A real U.S. company
Rx.com is headquartered in San Antonio, Texas, and helped people save on prescriptions long before we offered weight loss care. About us.
Licensed U.S. providers
Every visit is reviewed by a provider licensed in your state, with check-ins before refills and unlimited messaging with your care team.
Licensed U.S. pharmacy
Your medication is prepared for you by a state-licensed U.S. compounding pharmacy from a patient-specific prescription. Never "research use" products.
Prices on the page
No membership fee, no visit fee, no dose upcharge, no shipping charge. The plan price is what you pay, and it is printed above.
No auto-renew traps
Plans do not renew automatically. Refills ship only after you check in, and you can pause or cancel anytime with no fees.
What to check before you buy GLP-1s online
Whoever you choose, ask these questions. We built Rx.com so the answer is yes to every one.
See if I qualify| Rx.com | Many online programs | |
|---|---|---|
| LegitScript certified | ✓ | Not always |
| Same price at every dose | ✓ | Often more |
| Provider visit included | ✓ | Often extra |
| No membership fee | ✓ | Often extra |
| No automatic renewals | ✓ | Rarely |
| Only billed if prescribed | ✓ | Varies |
Prescribed by licensed providers. Supported the whole way.
This is a medical program, not a checkout button. A licensed provider decides whether a GLP-1 is safe for you, sets your dose, and adjusts it as you go.
- Provider review of your full health history
- Dose steps planned and adjusted by your provider
- Check-ins before every refill
- Unlimited messaging with your care team
Every dose. Everything included.
No membership fee, no separate medication bill, no dose upcharge. The number you see is the number you pay.
- Online visit with a licensed U.S. provider
- Your medication at any prescribed dose
- Ongoing check-ins and dose adjustments
- Syringes, alcohol pads and dosing guide
- Cold-packed, discreet shipping
- Unlimited messaging with your care team
“The signup process was easy, communication was clear, and I had everything shipped right to me.”
Tirzepatide vs. semaglutide
Our two medications, side by side. Your provider decides which, if either, is appropriate.
| Tirzepatide | Semaglutide | |
|---|---|---|
| What it acts on | GLP-1 and GIP receptors | GLP-1 receptor |
| How you take it | Once-weekly injection | Once-weekly injection |
| Dose range | 2.5 mg to 15 mg | 0.25 mg to 2.4 mg |
| Price | From $149/month | From $99/month |
Compounded medications are not FDA-approved; their safety and effectiveness have not been verified by the FDA, and they are not equivalent to any brand-name medication. Individual results vary.
Frequently asked questions
Is Rx.com legit?
What is a GLP-1 medication?
Semaglutide or tirzepatide: which should I choose?
What does the price include?
Does the price change as my dose goes up?
Do I need insurance?
Who qualifies?
What happens after I start?
Where is this available?
How do refills and cancellation work?
Important safety information
Boxed warning: semaglutide and tirzepatide caused thyroid C-cell tumors in rodent studies. It is not known whether they cause thyroid tumors, including medullary thyroid carcinoma, in people. Do not use them if you or any of your family have had medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2.
Common side effects include nausea, vomiting, diarrhea, constipation, stomach pain and decreased appetite, most often while your dose is being increased. Serious risks include pancreatitis, gallbladder disease, low blood sugar (especially with insulin or sulfonylureas), kidney injury from dehydration, and severe allergic reactions. Do not use if you are pregnant, breastfeeding or planning pregnancy, or under 18. Tell your provider about every medication and condition during your visit. This is not a complete list of risks.
Your next step is a 2-minute visit
Answer a few questions, and a licensed provider reviews your visit, usually within 24 hours. Not prescribed? You are not billed.
See if I qualify
Compounded semaglutide and tirzepatide are not FDA-approved and are not equivalent to any brand-name medication. Prescription required; a licensed provider determines eligibility and dose. Plans do not renew automatically; refills are sent only after you check in with your care team. Photos are of models and are for illustration only. Information on this page is educational and is not a substitute for advice from your own healthcare provider. See the Weight Loss Program page for the full program FAQ, pharmacy and provider details.
