Accrufer
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What is Accrufer?
Accrufer is a medication used to treat or prevent anemia, which is a condition where you have fewer red blood cells than normal. It helps your body produce more red blood cells by providing iron.
Side Effects
- Fever
- Shallow breathing, weakness, weak but fast heartbeat
- Pale or clammy skin
Warnings
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have stomach or intestinal problems, an active infection, diabetes, porphyria, or other medical problems.
- Make sure any doctor or dentist who treats you knows that you are using this medicine. Iron may affect the results of certain medical tests.
- Iron can cause your stools to be darker in color. This is normal and is not a cause for concern.
- Fever
- Pale or clammy skin
Prescription savings · · · ·
What is Accrufer ?
Accrufer is a medication used to treat or prevent anemia, which is a condition where you have fewer red blood cells than normal. It helps your body produce more red blood cells by providing iron.
- Fever
- Shallow breathing, weakness, weak but fast heartbeat
- Pale or clammy skin
- Severe or continuing stomach cramps, vomiting (with or without blood)
- Bloody diarrhea
- Bluish-colored lips, hands, or fingernails
- Chest pain
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have stomach or intestinal problems, an active infection, diabetes, porphyria, or other medical problems.
- Make sure any doctor or dentist who treats you knows that you are using this medicine. Iron may affect the results of certain medical tests.
- Iron can cause your stools to be darker in color. This is normal and is not a cause for concern.
- Fever
- Pale or clammy skin
- Severe or continuing stomach cramps, vomiting (with or without blood)
- Shallow breathing, weakness, weak but fast heartbeat
Accrufer Coupons & Prices
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Looking for an Accrufer coupon? Accrufer (ferric maltol) is a brand-only oral iron capsule with no generic version on the market, so the cash price you pay can vary a lot from one pharmacy to the next. Enter your ZIP code above to see today's Accrufer price at pharmacies near you and print, text, or show your free Rx.com discount card at the counter. There is no membership or signup, and the card can be used whether you have insurance, have Medicare, or are paying entirely out of pocket.
What is Accrufer and how does it work?
Accrufer is the U.S. brand name for ferric maltol, an oral iron replacement product. (In Europe and the UK the same medicine is sold as Feraccru.) Ferric maltol is a stable complex of ferric iron bound to three maltol molecules, and it is absorbed in the small intestine. It is FDA-approved to treat iron deficiency in adults and in children 10 years of age and older. It received its initial U.S. approval in 2019 from Shield Therapeutics for adults; the indication was later expanded to include pediatric patients 10 and older.
The recommended dose is 30 mg by mouth twice a day on an empty stomach, meaning 1 hour before or 2 hours after a meal. The capsules must be swallowed whole. Iron replacement is slow: generally at least 12 weeks of treatment is needed, and your provider will usually continue it until your ferritin level is back in the normal range. Accrufer is often chosen for people with iron deficiency anemia who cannot tolerate ordinary ferrous salt tablets, and its clinical development program was built largely in inflammatory bowel disease (Crohn's disease and ulcerative colitis) in remission.
Accrufer cost: manufacturer savings card vs. the Rx.com cash coupon
The Accrufer "coupon" search results are usually a mix of two very different things. The first is the manufacturer's official copay savings program, run by Shield Therapeutics and described on the official Accrufer website. Manufacturer copay cards like this are generally limited to people with commercial (employer or marketplace) insurance, and they typically exclude anyone with Medicare, Medicaid, TRICARE, or other government coverage. Eligibility rules, limits, and expiration terms vary and change, so read the program's own terms before counting on it. Ask your prescriber's office or the manufacturer whether a patient assistance program is available if you cannot afford the medication and do not qualify for the copay card.
The Rx.com cash coupon is a different tool and covers the gap the manufacturer card leaves. It is a cash-discount price, not insurance, so it works if you are uninsured, if you are on Medicare, or if the manufacturer card is declined at the pharmacy. It can also be worth checking even when you do have coverage, because a cash price is sometimes lower than a plan copay. Prices vary by pharmacy and by ZIP code, so enter your ZIP above to see today's price near you and compare before you fill. Since there is no generic ferric maltol on the market, comparing pharmacies is the main lever you have on the price of this specific product.
Is there a generic? Accrufer vs. other iron products
There is no FDA-approved generic ferric maltol marketed in the United States, so Accrufer is brand-only today. That is the single biggest reason it costs more than the familiar iron pills on the pharmacy shelf. If cost is a barrier, it is worth a conversation with your provider about whether a conventional oral iron salt is an option for you, since these are widely available:
The reason Accrufer exists is that a meaningful share of people cannot stay on ferrous salts because of stomach and bowel side effects, and stopping treatment means the iron deficiency never gets corrected. Other prescription iron options your provider may discuss include Auryxia (ferric citrate) and the intravenous iron Feraheme (ferumoxytol), which are different medicines with their own approved uses and are not interchangeable with Accrufer. You may also see this drug listed under its ingredient name, ferric maltol. Which product is right depends on your diagnosis, how severe the deficiency is, and how well you tolerate oral iron, so let your provider make that call.
Safety information you should know
Accrufer does not carry an FDA boxed warning. It should not be used by people who are allergic to ferric maltol or the capsule ingredients, who have hemochromatosis or another iron overload syndrome, or who receive repeated blood transfusions. The label warns that Accrufer may worsen inflammatory bowel disease, so it should be avoided during an active IBD flare. Because too much iron is harmful, your provider should check iron measures such as ferritin and transferrin saturation before you start and periodically during treatment, and stop the medicine if iron overload develops.
The most common side effects reported in more than 1% of patients are gas, diarrhea, constipation, dark or black stools, abdominal pain, nausea, vomiting, and abdominal discomfort or bloating. Dark stools are expected with iron and are not by themselves a cause for alarm. Stop taking Accrufer and get emergency care if you have trouble breathing or swelling of the face, lips, tongue, or throat, and tell your provider about any rash, hives, or itching. Accrufer should not be used with dimercaprol, and dosing should be separated by at least 4 hours from mycophenolate, ciprofloxacin, doxycycline, and products containing ethinyl estradiol; avoid taking other oral or IV iron products at the same time. Important: accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6, so keep this medicine out of reach of children and call poison control at 1-800-222-1222 right away if a child swallows any. This page is general information, not medical advice. Talk with your doctor or pharmacist about your own situation.
This Accrufer information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Accrufer on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.