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Candesartan Cilexetil-Hctz Tablet — prescription drug image

Candesartan Cilexetil-Hctz

Candesartan Cilexetil-HCTZ

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What is Candesartan Cilexetil-Hctz?

Atacand HCT is used to treat hypertension (high blood pressure). The generic version of Atacand HCT is Candesartan/Hydrochlorothiazide. The average Atacand HCT price is about $197 for a supply of 30, 32 mg/12.5 mg tablets. You can use our Single Care savings offer to get an average Atacand HCT discount of up to 80% off of the retail price at participating pharmacies near you.

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What is Candesartan Cilexetil-Hctz ?

Atacand HCT is used to treat hypertension (high blood pressure). The generic version of Atacand HCT is Candesartan/Hydrochlorothiazide. The average Atacand HCT price is about $197 for a supply of 30, 32 mg/12.5 mg tablets. You can use our Single Care savings offer to get an average Atacand HCT discount of up to 80% off of the retail price at participating pharmacies near you.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Lightheadedness, dizziness, or fainting
  • Eye pain, vision changes, seeing halos around lights
  • Confusion, weakness, uneven heartbeat, trouble breathing, numbness in your hands, feet, or lips
  • Dry mouth, increased thirst, muscle cramps, uneven heartbeat
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Change in how much or how often you urinate, problems urinating
  • Sores, reddish patch or irritated area, shiny bump, pink growth, or white, yellow or waxy scar-like area on the skin
  • Blistering, peeling, red skin rash
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • This medicine is not safe to take during pregnancy, especially in your second or third trimester. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding, or if you have kidney problems, liver disease, diabetes, gout, heart or blood vessel disease, heart failure, high cholesterol, lupus, trouble urinating, allergies, or a history of asthma.
  • This medicine may cause the following problems:Kidney problemsEye or vision problems, including glaucoma, myopiaChanges in blood sugar levelsIncreased risk for skin cancer
  • This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you feel lightheaded or dizzy.
  • Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in normal range. You may have to take blood pressure medicine for the rest of your life.
  • Drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting while you are using this medicine.
  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is candesartan cilexetil and hydrochlorothiazide used for?

It is FDA-approved to treat high blood pressure (hypertension) in adults. Lowering blood pressure reduces the risk of cardiovascular events such as stroke and heart attack. It is a fixed-dose combination of an ARB and a water pill, and it is not recommended as a starting blood pressure medicine. It is meant for people not adequately controlled on candesartan or hydrochlorothiazide alone, or as a replacement for taking the two separately. The combination product is approved for high blood pressure only, even though candesartan by itself also has a heart failure indication.

What are the side effects of candesartan and hydrochlorothiazide?

The label describes risks including dizziness or fainting from low blood pressure (most likely if you are dehydrated or low on salt), reduced kidney function in at-risk people, high potassium from the candesartan component, and low potassium, sodium, or magnesium from the hydrochlorothiazide component. Hydrochlorothiazide can also cause sun sensitivity, raise uric acid levels or trigger gout, worsen lupus, and has been associated with an increased risk of non-melanoma skin cancer. Rare but urgent problems include sudden nearsightedness or eye pain, which can mean acute angle-closure glaucoma. Report anything unusual to your doctor or pharmacist.

What is the generic for Atacand HCT?

The generic is candesartan cilexetil and hydrochlorothiazide. An FDA-approved generic version is available and can be substituted for brand-name Atacand HCT at the pharmacy. Cash prices for the generic still vary quite a bit between pharmacies, so it is worth comparing. Enter your ZIP code above to see today's price near you.

Is it better to take candesartan-HCTZ in the morning or at night?

There is no single right answer for everyone, and the label does not require a specific time of day. Because the hydrochlorothiazide component makes you urinate more, many people prefer taking it in the morning so they are not up at night. The most important thing is to take it at about the same time each day. Ask your doctor or pharmacist what timing fits your situation, and do not change your schedule on your own.

What foods and drugs should you avoid while taking candesartan and hydrochlorothiazide?

Tell your doctor about every medicine and supplement you take. Aliskiren should not be combined with this medicine if you have diabetes. Regular NSAID use, such as ibuprofen or naproxen, is generally best avoided in older adults or people with kidney problems taking it. Potassium supplements and potassium-containing salt substitutes can raise potassium too far because of the candesartan component, so check before using them. The hydrochlorothiazide component can make your skin more sensitive to sunlight, so use sun protection. Your doctor may also want to check your kidney function and electrolytes periodically.

How long does it take for candesartan-hydrochlorothiazide to lower blood pressure?

Blood pressure medicines in this class generally begin working within the first couple of weeks, with the fuller effect seen after several weeks of steady daily use. You will not feel the medicine working, which is why it is important to keep taking it as prescribed even when you feel fine, and to keep your follow-up appointments so your doctor can check your numbers and adjust treatment if needed.

How much does Candesartan Cilexetil-HCTZ 16-12.5MG cost without insurance?
The price of Candesartan Cilexetil-HCTZ 16-12.5MG without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Candesartan Cilexetil-HCTZ 16-12.5MG?
Common side effects of Candesartan Cilexetil-HCTZ 16-12.5MG may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Lightheadedness, dizziness, or fainting, Eye pain, vision changes, seeing halos around lights, Confusion, weakness, uneven heartbeat, trouble breathing, numbness in your hands, feet, or lips, Dry mouth, increased thirst, muscle cramps, uneven heartbeat. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Candesartan Cilexetil-HCTZ 16-12.5MG?
Generic versions may be available for Candesartan Cilexetil-HCTZ 16-12.5MG. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Candesartan Cilexetil-HCTZ 16-12.5MG on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Candesartan Cilexetil-HCTZ 16-12.5MG?
The cheapest pharmacy for Candesartan Cilexetil-HCTZ 16-12.5MG depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Candesartan Cilexetil-HCTZ 16-12.5MG near you.

Candesartan Cilexetil-Hctz Coupons & Prices

Candesartan Cilexetil-HCTZ

Prescriptions & Refills
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A candesartan-cilexetil-HCTZ coupon from Rx.com can lower what you pay at the pharmacy counter for the generic version of Atacand HCT, a two-in-one blood pressure tablet that combines candesartan cilexetil (an angiotensin II receptor blocker, or ARB) with hydrochlorothiazide (a thiazide diuretic, or water pill). Cash prices for this generic vary a lot from one pharmacy to the next, even between stores on the same street, so the pharmacy you choose matters. Rx.com compares prices across more than 60,000 pharmacies nationwide. Enter your ZIP code above to see today's price near you and print, text, or show your free coupon at the counter.

What is candesartan cilexetil and hydrochlorothiazide, and how does it work?

Candesartan cilexetil and hydrochlorothiazide is a fixed-dose combination tablet approved by the FDA to treat high blood pressure (hypertension) in adults. Lowering blood pressure reduces the risk of cardiovascular events such as stroke and heart attack. The two ingredients work in different ways. Candesartan is an angiotensin II receptor blocker (ARB), which relaxes blood vessels so blood flows more easily. Hydrochlorothiazide is a thiazide diuretic that helps your kidneys remove extra salt and water from the body. Common strengths include 16/12.5 mg, 32/12.5 mg, and 32/25 mg.

This combination is not recommended as the first medicine you try for high blood pressure. It is intended for people whose blood pressure is not adequately controlled on candesartan alone or hydrochlorothiazide alone, or as replacement therapy for people already taking the two medicines separately. One note worth knowing: candesartan by itself is also approved for certain kinds of heart failure, but the combination product with hydrochlorothiazide is approved for high blood pressure only.

What candesartan-HCTZ costs without insurance, and how to pay less

An FDA-approved generic of candesartan cilexetil and hydrochlorothiazide is available and can be substituted for the brand Atacand HCT at the pharmacy. But "generic" does not mean every pharmacy charges the same. Cash prices for the same strength and quantity can differ widely between chains, grocery store pharmacies, and independents, which is exactly why comparing before you fill is worth the two minutes. If you are paying without insurance, or if your plan's copay is higher than the cash price, a free discount coupon is often the cheaper path.

Rx.com is free to use, requires no signup, and compares prices at more than 60,000 pharmacies. Enter your ZIP code above to see today's price near you for your exact strength and quantity, then bring the coupon to the counter and ask the pharmacist to run it as cash discount instead of through your insurance. There is no manufacturer savings card for this generic combination. It is also worth asking whether a 90-day supply prices out better than a 30-day supply, since it often does.

Alternatives and similar blood pressure combinations

Candesartan-HCTZ is one of several ARB plus hydrochlorothiazide combination tablets. If your prescriber is considering options, or you want to compare cash prices across similar medicines, these are the closest relatives:

You can also compare the two ingredients on their own: candesartan cilexetil and hydrochlorothiazide. These medicines are not interchangeable, and only your prescriber can decide which is right for you. This page is for price comparison, not medical advice.

Safety information you should know

This medicine carries an FDA boxed warning for fetal toxicity: medicines that act on the renin-angiotensin system can injure or kill a developing baby. If you become pregnant, stop taking it and tell your doctor right away. It should not be used by anyone allergic to candesartan, hydrochlorothiazide, or other sulfonamide-derived drugs, or by anyone who is not producing urine (anuria). It should not be combined with aliskiren in people with diabetes.

Other risks listed on the label include low blood pressure with dizziness or fainting (especially if you are dehydrated or low on salt), reduced kidney function in people at risk, high potassium from candesartan, and low potassium, sodium, or magnesium from hydrochlorothiazide. Hydrochlorothiazide has also been linked to a higher risk of non-melanoma skin cancer, sun sensitivity, high uric acid or gout, and flare-ups of lupus. Sudden nearsightedness or eye pain can signal acute angle-closure glaucoma and needs immediate medical attention. Regular use of NSAIDs such as ibuprofen or naproxen should generally be avoided in older adults or those with kidney problems taking this medicine. This is a summary, not medical advice. Talk with your doctor or pharmacist about your full health history and every medicine you take.

Sources & accuracy

This Candesartan Cilexetil-Hctz information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Candesartan Cilexetil-Hctz on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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