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Ceftazidime

Ceftazidime

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What is Ceftazidime?

Ceftazidime is a third-generation cephalosporin antibiotic effective against a broad spectrum of Gram-negative bacteria, including Pseudomonas aeruginosa. It is commonly used in the treatment of severe respiratory, urinary tract, skin, and intra-abdominal infections, particularly those that are hospital-acquired. Ceftazidime works by disrupting the synthesis of the bacterial cell wall, leading to cell death.

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What is Ceftazidime ?

Ceftazidime is a third-generation cephalosporin antibiotic effective against a broad spectrum of Gram-negative bacteria, including Pseudomonas aeruginosa. It is commonly used in the treatment of severe respiratory, urinary tract, skin, and intra-abdominal infections, particularly those that are hospital-acquired. Ceftazidime works by disrupting the synthesis of the bacterial cell wall, leading to cell death.

  • Severe vomiting or stomach pain
  • Diarrhea that may contain blood
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Swelling, pain, or redness near where your IV is located
  • Blistering, peeling, red rash
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Tell your doctor if you are pregnant or breastfeeding, you had an allergic reaction to penicillin, you have kidney disease, liver disease, weak immune system, or you have a history of stomach or intestinal problems, including colitis.
  • This medicine may prevent birth control pills from working correctly. Use a second form of birth control while you are using this medicine.
  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is ceftazidime used to treat?

Ceftazidime is FDA-approved for serious infections caused by susceptible bacteria: lower respiratory tract infections including pneumonia (and infections in people with cystic fibrosis), skin and skin-structure infections, urinary tract infections, bacterial septicemia, bone and joint infections, gynecologic infections such as endometritis and pelvic cellulitis, intra-abdominal infections including peritonitis, and central nervous system infections including meningitis. It does not work against colds, the flu, or other viral infections.

Is ceftazidime a strong antibiotic, and does it cover Pseudomonas?

Yes. Ceftazidime is a third-generation cephalosporin with a broad spectrum, and it is specifically notable for its activity against Pseudomonas aeruginosa. That is why it is a mainstay of empiric anti-pseudomonal therapy in the hospital. Whether it is the right choice for a given infection depends on culture results and susceptibility testing, which your care team will use to guide treatment.

Can you take ceftazidime as a pill, or is it injection only?

Ceftazidime is injection only. It is given into a vein (IV) or into a muscle (IM), or as a premixed IV solution. There is no oral tablet, capsule, or liquid form of ceftazidime in the United States. If your prescriber wants an oral antibiotic, they would choose a different drug.

Can I take ceftazidime if I am allergic to penicillin?

Only your prescriber can make that call. Ceftazidime is a beta-lactam antibiotic, like penicillin, and cross-reactivity may occur in up to about 10% of penicillin-allergic patients, so a careful allergy history is required first. Ceftazidime should not be used in anyone who has had a serious hypersensitivity reaction to a cephalosporin. Tell your care team exactly what happened during any past reaction, such as rash, swelling, or trouble breathing.

What are the most common side effects of ceftazidime injection?

Frequently reported effects include pain, irritation, or phlebitis at the injection or IV site, diarrhea, nausea, rash, and temporary increases in liver enzymes. More serious but less common problems include severe allergic reactions, Clostridioides difficile-associated diarrhea or colitis (which may appear up to two months after treatment), severe skin reactions, rare hemolytic anemia or other blood problems, and neurologic toxicity such as seizures or confusion when the drug builds up in people with reduced kidney function. Call your provider about watery or bloody diarrhea, a spreading rash, or new confusion or twitching.

How is ceftazidime different from ceftriaxone and cefepime?

All three are injectable cephalosporins, but they cover different bacteria. Ceftazidime and ceftriaxone are both third-generation; ceftazidime is active against Pseudomonas aeruginosa, while ceftriaxone is not reliable against it. Cefepime is a fourth-generation cephalosporin that covers Pseudomonas like ceftazidime and adds more coverage of certain gram-positive bacteria. Your prescriber chooses among them based on the suspected or confirmed organism, the site of infection, your allergies, and your kidney function.

How much does cefTAZidime 1GM cost without insurance?
The price of cefTAZidime 1GM without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of cefTAZidime 1GM?
Common side effects of cefTAZidime 1GM may include: Severe vomiting or stomach pain, Diarrhea that may contain blood, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Swelling, pain, or redness near where your IV is located, Blistering, peeling, red rash. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of cefTAZidime 1GM?
Generic versions may be available for cefTAZidime 1GM. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search cefTAZidime 1GM on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for cefTAZidime 1GM?
The cheapest pharmacy for cefTAZidime 1GM depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for cefTAZidime 1GM near you.

Ceftazidime Coupons & Prices

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Use a free Rx.com ceftazidime coupon to compare cash prices on this injectable antibiotic at more than 60,000 pharmacies nationwide. Ceftazidime is the generic form of the third-generation cephalosporin sold under brand names such as Fortaz and Tazicef, and because the generic is widely available, the cash price is usually far below the brand. Prices still vary a great deal from one pharmacy to the next, even in the same town, so it pays to compare. Enter your ZIP code above to see today's ceftazidime price near you and print, text, or email your coupon at no cost.

What is ceftazidime and how does it work?

Ceftazidime is a third-generation cephalosporin antibiotic, part of the beta-lactam family. It kills bacteria by interfering with the way they build their cell walls, so the bacteria cannot hold together and survive. It is best known for being active against Pseudomonas aeruginosa, a hard-to-treat bacterium, which is why it is a mainstay when doctors need broad anti-pseudomonal coverage.

Ceftazidime is given only by injection into a vein (IV) or into a muscle (IM), or as a premixed IV solution. There is no pill or liquid form you can swallow. The FDA has approved it for serious infections caused by susceptible bacteria, including lower respiratory tract infections such as pneumonia (including infections in people with cystic fibrosis), skin and skin-structure infections, urinary tract infections, bacterial septicemia, bone and joint infections, gynecologic infections, intra-abdominal infections such as peritonitis, and central nervous system infections including meningitis. Like all antibiotics, ceftazidime does not treat colds, the flu, or other viral illnesses.

Ceftazidime cost and how to save without insurance

Ceftazidime is available as an FDA-approved generic, so it is already one of the lower-cost options in its class compared with brand-name Fortaz or Tazicef. Even so, the cash price for the same vial and the same strength can differ widely from pharmacy to pharmacy, which is exactly why comparing before you fill matters. Rx.com checks prices across more than 60,000 pharmacies and shows you the discounted cash price at each one.

A few honest notes if you are paying without insurance. Ceftazidime is an injectable drug, so it is often given in a hospital, clinic, or infusion center, and in that setting it is billed as part of your care rather than picked up at a retail counter. If your prescriber sends ceftazidime to a retail or home-infusion pharmacy, a discount coupon can be used there. There is no manufacturer savings card for generic ceftazidime. Our coupon is free, requires no membership, and can be used instead of insurance if the cash price is lower. Enter your ZIP above to see today's price near you.

Ceftazidime vs. other cephalosporins and alternatives

Cephalosporins are grouped by "generations," and each generation covers a somewhat different set of bacteria. Your prescriber picks one based on the infection, the likely bacteria, your allergy history, and your kidney function. Ceftazidime's distinguishing feature is its anti-pseudomonal activity.

  • Cefepime is a fourth-generation cephalosporin that also covers Pseudomonas and adds more coverage of certain gram-positive bacteria.
  • Ceftriaxone is a third-generation cephalosporin used very widely, but it is not reliable against Pseudomonas. It can often be given once a day.
  • Cefotaxime is another third-generation injectable cephalosporin without anti-pseudomonal coverage.
  • Cefazolin is a first-generation cephalosporin used mainly for skin infections and surgical prevention.
  • Cefuroxime is a second-generation cephalosporin available in both injectable and oral forms.
  • Ciprofloxacin is a fluoroquinolone (a different class) that also has activity against Pseudomonas and comes in oral and IV forms.

Ceftazidime is also one half of the separate combination brand drug Avycaz (ceftazidime/avibactam), which pairs it with a beta-lactamase inhibitor. Avycaz is its own brand product and is not interchangeable with plain ceftazidime. These drugs are not swappable on your own, so never substitute one antibiotic for another without your prescriber.

Ceftazidime safety and side effects

Ceftazidime has no boxed warning, but there are important risks to know about. Serious allergic reactions, including anaphylaxis, can happen, so tell your care team about any prior reaction to a cephalosporin or penicillin. Cross-reactivity may occur in up to about 10% of people who are allergic to penicillin, so a careful allergy history is required before the first dose. Antibiotics such as ceftazidime can also cause Clostridioides difficile-associated diarrhea and pseudomembranous colitis, which can be serious and may appear up to two months after treatment ends. Report any watery or bloody diarrhea to your provider rather than treating it yourself.

Ceftazidime is cleared by the kidneys, and if it builds up in people with reduced kidney function it can cause neurologic problems such as seizures, nonconvulsive status epilepticus, encephalopathy, coma, asterixis, muscle twitching, or myoclonia. The dose must be lowered based on creatinine clearance, so your kidney function should be checked. Other reported effects include injection-site pain or vein irritation, rash, transient increases in liver enzymes, rare hemolytic anemia and other blood problems (prothrombin time may be monitored in at-risk patients), severe skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, or DRESS, and overgrowth of organisms the drug does not cover. Kidney-injury risk goes up when ceftazidime is used with aminoglycoside antibiotics or potent diuretics, and ceftazidime may reduce the effectiveness of some oral contraceptives. Finish the entire prescribed course, even if you feel better. This page is general information, not medical advice; talk with your doctor or pharmacist about your own situation.

Sources & accuracy

This Ceftazidime information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Ceftazidime on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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