Minocycline Hcl
Minocycline HCl 100MG
What is Minocycline Hcl?
Minocin is used to treat bacterial infections. Minocycline is the generic version. On average Minocin is priced at about $2,900 for a supply of 60, 100 mg oral capsules. Luckily, you can use our Rx.com savings offer to receive a Minocin discount of up to 80% off the retail price at participating pharmacies near you.Side Effects
- Severe diarrhea, stomach cramps
- Headache, vision changes, blurred vision
- Change in how much or how often you urinate
Warnings
- This medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. Birth control pills may not work as well while you are using this medicine. Use a second form of birth control until your treatment ends.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, asthma, or an allergy to sulfites.
- This medicine may cause the following problems:Permanent change in tooth color (in children younger than 8 years old)Drug reaction with eosinophilia and systemic symptoms (DRESS), which may damage organs such as the liver, kidney, or heartIntracranial hypertension (increased pressure in the head)
- This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
Prescription savings · · · ·
What is Minocycline Hcl ?
Minocin is used to treat bacterial infections. Minocycline is the generic version. On average Minocin is priced at about $2,900 for a supply of 60, 100 mg oral capsules. Luckily, you can use our Rx.com savings offer to receive a Minocin discount of up to 80% off the retail price at participating pharmacies near you.- Severe diarrhea, stomach cramps
- Headache, vision changes, blurred vision
- Change in how much or how often you urinate
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Joint pain, fever, rash, unusual tiredness or weakness
- Swollen glands in the armpits, neck, or groin
- This medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. Birth control pills may not work as well while you are using this medicine. Use a second form of birth control until your treatment ends.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, asthma, or an allergy to sulfites.
- This medicine may cause the following problems:Permanent change in tooth color (in children younger than 8 years old)Drug reaction with eosinophilia and systemic symptoms (DRESS), which may damage organs such as the liver, kidney, or heartIntracranial hypertension (increased pressure in the head)
- This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
- This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Minocycline Hcl Coupons & Prices
Minocycline HCl 100MG
Minocycline HCl is a widely prescribed tetracycline-class antibiotic, and it's already available as an FDA-approved generic at pharmacies nationwide — but the price for the exact same prescription can still vary a lot depending on where you fill it. Rx.com compares prices across more than 60,000 U.S. pharmacies, so before you search for a minocycline HCl coupon elsewhere, enter your ZIP code above to see today's price at pharmacies near you.
What Is Minocycline HCl?
Minocycline hydrochloride is a tetracycline-class antibiotic sold under the brand name Minocin (also marketed as Dynacin, Vectrin, and Myrac). It's FDA-approved to treat bacterial infections susceptible to tetracyclines, including respiratory tract infections, urinary tract infections, and skin and skin-structure infections, as well as infections spread by ticks, lice, or mites (such as Rocky Mountain spotted fever, typhus, and Lyme disease), chlamydia, gonorrhea (as an alternative option), and severe acne vulgaris. Doctors also sometimes prescribe it off-label, often at a lower dose, for moderate-to-severe acne and rosacea, and off-label as an add-on for rheumatoid arthritis or for MRSA skin infections — your provider can tell you whether an off-label use makes sense for your situation.
The same active ingredient is also used in other, separate products: extended-release tablets (marketed under brand names such as Solodyn, Ximino, and Minolira) approved specifically for acne, topical foams (Amzeeq for acne, Zilxi for rosacea) applied to the skin, and a dental product (Arestin) placed directly into gum pockets. Those are different formulations and different prescriptions — this page is for the immediate-release oral minocycline HCl capsule or tablet.
Minocycline HCl Cost: Why Comparing Pharmacies Matters
Minocycline HCl is an FDA-approved generic, which generally means it's more accessible than a brand-only drug — but that doesn't mean every pharmacy charges the same amount. Cash prices for generic antibiotics can differ significantly from one pharmacy to the next based on the pharmacy's own pricing, your dosage, and the quantity prescribed, so it's worth comparing before you fill.
Rx.com checks pricing at more than 60,000 pharmacies across the country, including major chains and independent pharmacies, so you can see today's price and a minocycline HCl coupon at pharmacies near you. Enter your ZIP code above to compare.
Minocycline vs. Other Antibiotics
Minocycline belongs to the tetracycline class of antibiotics, alongside doxycycline (including the doxycycline hyclate salt form) and tetracycline itself. These three drugs treat overlapping types of bacterial infections and are all used for acne, but they are not interchangeable — dosing, side-effect profile, and which infections they're approved for differ, and your provider will choose based on your specific diagnosis, kidney function, and other medications you take.
Minocycline and doxycycline are the two tetracyclines most commonly compared for acne and skin infections. For infections outside the tetracycline class, a provider might instead consider an antibiotic like amoxicillin or clindamycin, depending on the type of infection being treated. Only your prescriber can determine which antibiotic is right for you — this is general information, not a substitute for medical advice.
Minocycline HCl Safety Information
Minocycline HCl's label does not carry an FDA boxed warning, but it does carry several important precautions patients should know about:
- Should be avoided in pregnancy and in children under 8 — tetracyclines can permanently discolor developing teeth and affect bone growth
- Can increase sensitivity to sunlight (photosensitivity)
- With long-term use, has been linked to a lupus-like syndrome and to autoimmune hepatitis
- Carries a risk of intracranial hypertension (pseudotumor cerebri), which is higher when taken together with isotretinoin
- Can cause hypersensitivity reactions, including the rare but serious DRESS syndrome
- May reduce the effectiveness of hormonal birth control
- Can cause dizziness or vertigo, reported more often in women
- Should be used cautiously in people with kidney or liver problems
- Like other antibiotics, can cause C. difficile-associated diarrhea and contribute to antibiotic resistance if overused
This isn't a complete list of warnings or side effects. Read the full prescribing information and talk with your provider or pharmacist about your health history before starting minocycline — this content is for general education and isn't medical advice.
This Minocycline Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Minocycline Hcl on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.