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Qbrexza

Qbrexza 30 Pad

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What is Qbrexza?

Qbrexza (glycopyrronium) is a topical anticholinergic cloth used to treat excessive underarm sweating (primary axillary hyperhidrosis) in adults and children aged 9 years and older. Each medicated cloth, packaged for single-use application, works by inhibiting the action of acetylcholine on sweat glands, thus reducing sweating in the applied area.

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What is Qbrexza ?

Qbrexza (glycopyrronium) is a topical anticholinergic cloth used to treat excessive underarm sweating (primary axillary hyperhidrosis) in adults and children aged 9 years and older. Each medicated cloth, packaged for single-use application, works by inhibiting the action of acetylcholine on sweat glands, thus reducing sweating in the applied area.
  • Blurred vision
  • Unable to sweat, feeling overheated, unexplained high fever
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, difficult or painful urination
  • This medicine may keep you from sweating enough, which may cause your body to get too hot. Be careful in hot weather, and while you exercise or use a sauna or whirlpool.
  • This medicine may cause blurred vision. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, prostate or bladder problems, or trouble passing urine.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
  • This medicine may cause urinary retention (trouble passing urine or not fully emptying the bladder).
What is Qbrexza used for?
Qbrexza is FDA-approved for the topical treatment of primary axillary hyperhidrosis, meaning excessive underarm sweating, in adults and children 9 years of age and older. It's applied once daily to both underarms using a single pre-moistened cloth. It is not approved for use on other areas of the body, such as the palms, soles, or face.
How does Qbrexza (glycopyrronium) work to stop sweating?
Qbrexza contains glycopyrronium (glycopyrronium tosylate), an anticholinergic medication that blocks M1 and M3 muscarinic receptors in the skin. This interrupts the nerve signal that normally tells underarm sweat glands to produce sweat, reducing sweat output where it's applied.
What are the side effects of Qbrexza?
The most common side effects reported in clinical trials (each in more than 2% of patients) are anticholinergic in nature: dry mouth, mydriasis (pupil dilation), oropharyngeal pain, headache, urinary hesitation, and blurred vision. The product is also flammable due to its alcohol content, and because it can reduce sweating, it's important to avoid strenuous activity in hot environments. Qbrexza is contraindicated in people with glaucoma, paralytic ileus, unstable cardiovascular status in acute hemorrhage, severe ulcerative colitis or toxic megacolon, myasthenia gravis, or Sjögren's syndrome, so it should not be used in patients with these conditions. The label separately advises caution for patients with a prior history of urinary retention. Talk to your provider about your full medical history before starting.
Is there a generic version of Qbrexza?
No. There is currently no FDA-approved generic version of Qbrexza (topical glycopyrronium cloth), so the brand-name product is the option available at the pharmacy. Cash prices can still vary by pharmacy, so it's worth comparing.
How much does Qbrexza cost and are there savings cards or coupons?
Pricing varies by pharmacy and insurance coverage, so enter your ZIP above to see today's Qbrexza price near you. The manufacturer also offers its own savings program through getqbrexza.com, which is generally limited to patients with commercial insurance and has terms that can change. If you're uninsured, on Medicare, or the manufacturer card doesn't apply to you, an Rx.com cash coupon is worth comparing at the pharmacy counter.
Can Qbrexza be used on areas other than the underarms?
No. Qbrexza is FDA-approved only for use on the underarms (axillary hyperhidrosis). It is not approved for other areas such as the palms, soles, or face, though some off-label use on other sweating sites has been reported anecdotally; that would be a decision to discuss with your provider, not an FDA-approved use.
How much does Qbrexza cost without insurance?
The price of Qbrexza without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Qbrexza?
Common side effects of Qbrexza may include: Blurred vision, Unable to sweat, feeling overheated, unexplained high fever, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Change in how much or how often you urinate, difficult or painful urination. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Qbrexza?
Generic versions may be available for Qbrexza. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Qbrexza on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Qbrexza?
The cheapest pharmacy for Qbrexza depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Qbrexza near you.

Qbrexza Coupons & Prices

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If you're searching for a Qbrexza coupon, there are two paths worth comparing: the manufacturer's savings program for commercially insured patients, or a cash-price coupon on Rx.com that works even without insurance. Qbrexza (glycopyrronium) is an FDA-approved topical treatment for excessive underarm sweating (primary axillary hyperhidrosis) in adults and children 9 years of age and older, applied once daily using a single pre-moistened cloth. Enter your ZIP above to see today's Qbrexza price at pharmacies near you.

What Is Qbrexza and How Does It Work?

Qbrexza is the brand name for glycopyrronium (glycopyrronium tosylate), a topical anticholinergic (antimuscarinic) medication that blocks M1 and M3 muscarinic receptors in the skin. This action interrupts the nerve signal that triggers sweat glands, reducing underarm sweat production. It comes as a 2.4% solution on a single-use, pre-moistened cloth applied to both underarms once daily.

Qbrexza is FDA-approved specifically for primary axillary hyperhidrosis (excessive underarm sweating) in adults and pediatric patients 9 years of age and older. It is not approved for use on other areas of the body, such as the palms, soles, or face.

Qbrexza Coupon: Manufacturer Savings Card vs. Rx.com Cash Price

Qbrexza does not currently have an FDA-approved generic, so the brand-name product is what most patients are pricing out, which makes finding the lowest price at the counter especially worthwhile. The manufacturer offers an official Qbrexza savings program through its own site (getqbrexza.com); like most manufacturer copay cards, it's generally limited to patients with commercial insurance, and eligibility and terms can change, so confirm the current details directly with the manufacturer before assuming you qualify.

If you're uninsured, on Medicare (which typically can't use manufacturer copay cards), or the manufacturer's card is declined at the pharmacy, an Rx.com cash coupon is worth comparing. Enter your ZIP above to see today's price at pharmacies near you, since cash prices for Qbrexza vary by pharmacy.

Other Options for Excessive Sweating

Qbrexza isn't the only prescription option for excessive sweating. Botox (onabotulinumtoxinA) is FDA-approved as an injectable treatment for severe primary axillary hyperhidrosis when topical treatments haven't given enough relief; it's a different route of administration than Qbrexza's daily cloth and a separate conversation to have with your provider. Prescription topical antiperspirants containing aluminum chloride, such as the brand Drysol or generic aluminum chloride solutions, are also commonly used and are often tried before or alongside Qbrexza. Oral glycopyrronium (glycopyrrolate) products are a related but distinct formulation taken by mouth rather than applied to the skin; they are not a direct substitute for Qbrexza's topical cloth. A provider can help determine which approach fits your situation.

Qbrexza Safety Information and Side Effects

Because Qbrexza is an anticholinergic medication, its most common side effects come from blocking acetylcholine activity elsewhere in the body. In clinical trials, the most frequently reported reactions (each occurring in more than 2% of patients) included dry mouth, mydriasis (pupil dilation), oropharyngeal pain, headache, urinary hesitation, and blurred vision. Qbrexza is contraindicated in people with glaucoma, paralytic ileus, unstable cardiovascular status in acute hemorrhage, severe ulcerative colitis or toxic megacolon complicating ulcerative colitis, myasthenia gravis, or Sjögren's syndrome; it should not be used in patients with these conditions. Separately, the label advises caution in patients with a prior history of urinary retention specifically, since Qbrexza's anticholinergic effect can worsen that risk. Tell your provider about your full medical history before starting treatment.

The solution is flammable because it contains alcohol, so keep it away from heat or open flame until it dries. Because it can reduce how much you sweat, avoid strenuous activity in hot environments, since this can raise the risk of overheating. Wash your hands thoroughly after applying the cloth and avoid touching your eyes or other mucous membranes, since transferred product can cause temporary blurred vision or pupil dilation. This is general information, not medical advice; always follow your provider's guidance and the product label.

Sources & accuracy

This Qbrexza information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Qbrexza on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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