Acyclovir Coupons & Prices

Looking for an acyclovir coupon? Acyclovir is the low-cost generic antiviral (brand names Zovirax and Sitavig) used to treat herpes simplex infections, shingles, and chickenpox. Because it is a widely stocked generic, cash prices can still swing a lot from one pharmacy to the next, so comparing before you fill matters. Rx.com checks prices across more than 60,000 U.S. pharmacies so you can find a low price near you. Enter your ZIP above to see today's acyclovir price and print or text yourself a free coupon.

What is acyclovir and how does it work?

Acyclovir is a synthetic nucleoside (guanine) analogue in the antiviral drug class. It works by interfering with the herpes virus's ability to copy its own DNA, which slows the spread of the infection and helps sores heal. It does not cure herpes and does not stop you from passing the virus to others.

It is FDA-approved to treat herpes simplex virus (HSV) infections, including initial and recurrent genital herpes and cold sores (herpes labialis, treated with the topical cream), as well as mucocutaneous HSV in people with weakened immune systems. It is also approved to treat herpes zoster (shingles) and chickenpox (varicella). Acyclovir comes in several forms, including oral tablets and capsules, topical cream, ophthalmic (eye), buccal, and intravenous (IV) versions given in a hospital.

How much does acyclovir cost without insurance?

Acyclovir is available as a generic (generic_available: yes), so it is generally one of the more affordable antivirals to buy with cash. That said, the sticker price without insurance is not the same everywhere: two pharmacies in the same town can quote very different cash prices for the exact same tablets. That is why it pays to compare rather than fill at the first pharmacy you see.

Rx.com compares live acyclovir prices across 60,000+ pharmacies and turns the lowest one into a free coupon you can use at the counter. We do not list fixed dollar amounts here because prices change often and depend on your ZIP code, the form (tablet, cream, or capsule), and the strength you are prescribed. Enter your ZIP above to see today's price near you.

Acyclovir vs. valacyclovir, famciclovir, and other alternatives

Acyclovir belongs to the same family as several other antivirals your provider may consider. Valacyclovir (brand Valtrex) is a prodrug of acyclovir that the body converts to acyclovir, and it is often dosed less frequently. Famciclovir is another oral option in the same category. Ganciclovir is a related antiviral used for different viral infections. The brand version of acyclovir itself is Zovirax.

Which one is right for you depends on your diagnosis, how often you would need to take it, and cost. Because all of these can vary in price, it is worth comparing the generic and its alternatives. Enter your ZIP above to see current prices for acyclovir and its relatives, and talk with your provider or pharmacist about which fits your treatment plan.

Acyclovir safety and side effects

Acyclovir has no FDA boxed warning, but there are important safety points to know. It can affect the kidneys (acute kidney injury), especially with IV use, higher doses, or if you are dehydrated, so staying well hydrated matters. In some people, particularly those with reduced kidney function, it can cause neurologic effects such as confusion, hallucinations, agitation, or seizures; your dose may need to be lowered if you have kidney disease. Rare but serious blood disorders (TTP/HUS) have been reported in people who are immunocompromised, and hypersensitivity (allergic) reactions can occur.

This is general information, not medical advice. Acyclovir does not cure herpes and does not prevent spreading it to others. Tell your provider about your kidney health and any other medicines you take, and follow their dosing instructions and hydration guidance. Contact your provider or pharmacist with questions or if you notice worrying symptoms.