What is Apriso ?

Mesalamine ER (extended-release) is an anti-inflammatory medication used primarily to treat and manage mild to moderate ulcerative colitis, a type of inflammatory bowel disease. It works by reducing inflammation in the colon, helping to relieve symptoms such as diarrhea, rectal bleeding, and stomach pain. Designed for prolonged action, the extended-release formulation ensures consistent therapeutic levels of mesalamine in the digestive tract over an extended period.

• Headache
• Nausea
• Abdominal pain
• Diarrhea
• Vomiting
• Flatulence
• Dizziness

• Hypersensitivity reactions can occur, including myocarditis and pericarditis.
• Caution advised in patients with history of renal impairment.
• May cause acute exacerbation of ulcerative colitis symptoms.
• Monitor liver function in patients with liver disease.
• Potential for serious skin reactions including Stevens-Johnson syndrome and toxic epidermal necrolysis.
• Use with caution in patients with pre-existing skin conditions.
• Risk of mesalamine-induced acute intolerance syndrome characterized by cramping, acute abdominal pain, and bloody diarrhea.