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Ketoprofen Jar — prescription drug image

Ketoprofen

Ketoprofen

What is Ketoprofen?

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain caused by arthritis. Ketoprofen is a generic drug. The average Ketoprofen price is about $36 for a supply of 30, 75 mg oral capsules. You can use our Rx.com savings offer to get an average Ketoprofen discount of up to 80% off of the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Ketoprofen ?

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain caused by arthritis. Ketoprofen is a generic drug. The average Ketoprofen price is about $36 for a supply of 30, 75 mg oral capsules. You can use our Rx.com savings offer to get an average Ketoprofen discount of up to 80% off of the retail price at participating pharmacies near you.

  • Gastrointestinal discomfort
  • Headache
  • Dizziness
  • Nausea
  • Diarrhea
  • Rash
  • Edema
  • Fatigue
  • Increased risk of gastrointestinal bleeding
  • Potential kidney damage with long-term use
  • Not recommended for use during late pregnancy
  • Risk of serious cardiovascular thrombotic events
  • Do not use with other NSAIDs or aspirin without medical advice
  • May cause allergic reactions in those allergic to aspirin
  • Risk of liver enzymes elevations
  • Caution should be exercised in patients with asthma
What is ketoprofen used for?

Prescription ketoprofen capsules are FDA-approved to relieve the signs and symptoms of rheumatoid arthritis and osteoarthritis. The immediate-release capsules are also approved for mild to moderate pain and for primary dysmenorrhea (menstrual cramps). The extended-release once-daily capsule is only for rheumatoid arthritis and osteoarthritis, not for short-term pain. Ketoprofen should not be used for pain around coronary artery bypass graft (CABG) heart surgery.

Is ketoprofen stronger than ibuprofen or naproxen?

They are all NSAIDs in the same propionic acid family and work the same basic way, so it is not accurate to rank one as simply stronger. They differ in the usual dose, how long each dose lasts, and how well an individual tolerates them. Response is personal: someone who gets little relief from one NSAID may do better on another. Your prescriber picks based on your condition, your other medicines, and your heart, kidney, and stomach risk. Do not take two NSAIDs at once.

How long does it take ketoprofen to work, and how long does it last?

For pain, immediate-release ketoprofen capsules are absorbed quickly, and relief usually begins within about an hour of a dose; in the studies behind the label, many patients reported some pain relief within 30 minutes. Blood levels peak roughly a half hour to two hours after a dose, and for pain the label directs doses every 6 to 8 hours as needed. The extended-release capsule is designed to be taken once daily and is used only for arthritis. For arthritis, the full anti-inflammatory benefit can take longer than a single dose to show up, so give it the time your prescriber recommends before judging whether it is working. Do not take an extra dose to speed things up. Follow the exact schedule on your label.

Is ketoprofen available over the counter?

Not anymore in the United States. Lower-dose 12.5 mg over-the-counter ketoprofen products such as Orudis KT and Actron were sold in the past, but they have been discontinued. Today ketoprofen is available only by prescription, as a generic. Compounded topical ketoprofen creams and gels are not FDA-approved in the U.S. If you want an over-the-counter NSAID, ibuprofen and naproxen are still sold that way.

Who should not take ketoprofen?

Do not take ketoprofen if you have ever had asthma, hives, or another allergic-type reaction after taking aspirin or another NSAID. It should not be used for pain around CABG heart surgery, and it should be avoided starting at 20 weeks of pregnancy or later. Talk with your doctor first if you have heart disease, high blood pressure, a history of stomach ulcers or bleeding, kidney or liver disease, or if you take blood thinners, antiplatelet drugs, SSRIs, or steroids. The label also calls for a smaller starting dose in small or debilitated (frail) individuals, in elderly patients, and in people with kidney or liver disease. This is general information, not medical advice.

How much does Ketoprofen 25GM of cost without insurance?
The price of Ketoprofen 25GM of without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Ketoprofen 25GM of ?
Common side effects of Ketoprofen 25GM of may include: Gastrointestinal discomfort, Headache, Dizziness, Nausea, Diarrhea. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Ketoprofen 25GM of ?
Generic versions may be available for Ketoprofen 25GM of . Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Ketoprofen 25GM of on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Ketoprofen 25GM of ?
The cheapest pharmacy for Ketoprofen 25GM of depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Ketoprofen 25GM of near you.

Ketoprofen Coupons & Prices

Ketoprofen

Ketoprofen Jar — prescription drug image
Prescription
Ketoprofen 100gm of (0.3)
your area ·

Ketoprofen prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
1gm of · Bottle 100 $508.67
5gm of · Bottle 30 $433.99 $362.46
25gm of · Bottle 60 $124.39 $65.71
100gm of · Bottle 60 $516.00
500gm of · Bottle 60 $738.50
1000gm of · Bottle 60 $738.50
5000gm of · Bottle 100 $856.68

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for a ketoprofen coupon? Ketoprofen is a prescription nonsteroidal anti-inflammatory drug (NSAID) used to relieve the signs and symptoms of rheumatoid arthritis and osteoarthritis, and, in the immediate-release capsule form, mild to moderate pain and menstrual cramps. It is sold only as a generic in the U.S. today, and the cash price still swings a lot from one pharmacy counter to the next in the same town. Rx.com compares cash prices at more than 60,000 pharmacies and gives you a free discount coupon you can hand to the pharmacist. Enter your ZIP code above to see today's ketoprofen price near you.

What is ketoprofen and how does it work?

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) in the propionic acid family, the same broad family as ibuprofen and naproxen. It works by blocking COX-1 and COX-2, two enzymes your body uses to make prostaglandins. Prostaglandins are the chemical messengers that drive pain, swelling, and fever, so turning them down eases joint pain and inflammation.

Prescription ketoprofen capsules are FDA-approved to relieve the signs and symptoms of rheumatoid arthritis and osteoarthritis. Immediate-release capsules are also approved for mild to moderate pain and for primary dysmenorrhea (menstrual cramps). The extended-release, once-daily capsule is approved only for rheumatoid arthritis and osteoarthritis, not for short-term or acute pain. Ketoprofen must not be used for pain around coronary artery bypass graft (CABG) heart surgery.

Ketoprofen cost and coupons without insurance

There is no brand of ketoprofen on the U.S. market anymore. Orudis, Oruvail, Actron, Orudis KT, and Nexcede have all been discontinued, so only generic ketoprofen remains. Because ketoprofen is generic-only, there is no manufacturer savings card to chase, which makes a cash discount coupon the main way to bring the price down.

The catch is that cash prices for the same generic capsule are set independently by each pharmacy chain, and they are not close to each other. Two stores a few miles apart can charge very different amounts for the identical bottle. Prices vary by pharmacy and by location, so it is worth comparing before you fill.

  • Enter your ZIP code above to see today's ketoprofen price at pharmacies near you.
  • Print, text, or show the free Rx.com coupon at the counter. There is no membership fee and no insurance needed.
  • Ask the pharmacist to run the coupon as a cash discount. Sometimes that beats your insurance copay, so it is fair to ask which is lower.
  • Ask your prescriber whether a larger day supply (for example a 90-day fill) makes sense for an ongoing arthritis prescription, since the per-capsule cost often drops.

Ketoprofen vs. other NSAIDs

Ketoprofen is one of many NSAIDs, and all of them share the same basic mechanism and the same class-wide heart and stomach risks. Which one works best is very individual: people who get little relief from one NSAID sometimes do well on another, so prescribers often try a different agent rather than pushing the dose higher. Common alternatives, all available as generics, include:

  • Ibuprofen and naproxen — the most familiar propionic acid NSAIDs; both also come in lower-strength over-the-counter versions.
  • Meloxicam and nabumetone — once-daily options often used for ongoing arthritis.
  • Diclofenac and etodolac — other prescription NSAIDs for osteoarthritis and rheumatoid arthritis.
  • Indomethacin — a potent older NSAID.
  • Celecoxib — a COX-2 selective NSAID, which is sometimes chosen when stomach tolerance is the main concern.

Never take two NSAIDs at the same time, including over-the-counter ibuprofen or naproxen on top of prescription ketoprofen. If cost is what is driving the question, compare the cash price of each option on Rx.com before you and your prescriber decide.

Ketoprofen safety: what to know

Ketoprofen carries two FDA boxed warnings that apply to NSAIDs as a class. First, cardiovascular thrombotic events: NSAIDs raise the risk of serious and potentially fatal heart attack and stroke. The risk may increase the longer you use the drug and is higher in people who already have heart disease or heart risk factors. Ketoprofen is contraindicated for pain around CABG heart surgery. Second, gastrointestinal bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal, can happen at any time and without warning symptoms; older adults are at the greatest risk.

Other important cautions: do not take ketoprofen if you have had asthma, hives, or an allergic-type reaction after aspirin or another NSAID. It can cause kidney injury (especially in older adults, in dehydration or heart failure, or when taken with ACE inhibitors, ARBs, or diuretics), fluid retention and swelling, new or worsening high blood pressure, liver injury, and rarely serious skin reactions. It also thins the blood by blocking platelets, so bleeding risk goes up with anticoagulants, antiplatelet drugs, SSRIs, or steroids. Avoid ketoprofen starting at 20 weeks of pregnancy or later. The label directs that a smaller starting dose be used in small or debilitated (frail) individuals, in elderly patients, and in people with kidney or liver disease. Use the lowest dose that works, for the shortest time. This is general information, not medical advice. Talk with your doctor or pharmacist about your own health history before starting or stopping ketoprofen.

Sources & accuracy

This Ketoprofen information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Ketoprofen on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.