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Tivicay Tablet — prescription drug image

Tivicay

Tivicay 50MG

What is Tivicay?

Tivicay is an antiviral medication that prevents HIV from multiplying in your body. Both adults and children (who weigh at least 66 pounds) can take the medication. Currently, there is not a generic version of Tivicay. The average cash price is $1,961 for a supply of 30, 50 mg tablets. However, thanks to Singlecare, as much as 75% of the cost of Tivicay can be reduced.

Prescription savings · · · ·

What is Tivicay ?

Tivicay is an antiviral medication that prevents HIV from multiplying in your body. Both adults and children (who weigh at least 66 pounds) can take the medication. Currently, there is not a generic version of Tivicay. The average cash price is $1,961 for a supply of 30, 50 mg tablets. However, thanks to Singlecare, as much as 75% of the cost of Tivicay can be reduced.
  • Fever, chills, cough, sore throat, joint or muscle aches, unusual tiredness or weakness
  • Redness, pain, or swelling of or around your eye or eyelid
  • Blistering, peeling, or severe skin rash
  • Sores on your lips or mouth
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Always practice safe sex, even if your partner also has HIV. If you stop taking this medicine or do not take it as prescribed, you may spread HIV to others. Do not reuse or share needles, or other items, that may have blood or body fluids on them.
  • This medicine may cause the following problems:Serious skin reactionsLiver problems
  • Your immune system may get stronger when you start taking HIV medicines. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.
  • Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.
  • Tell your doctor if you have kidney disease, liver disease (including hepatitis B or C), or other types of infection.
  • Using this medicine while you are pregnant can harm your unborn baby. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting treatment. Do not use this medicine during the first part of your pregnancy. Use an effective form of birth control to keep from getting pregnant. Tell your doctor right away if you think you have become pregnant.
What is Tivicay (dolutegravir) used for?
Tivicay contains dolutegravir, an HIV integrase inhibitor. It's FDA-approved, in combination with other antiretroviral medications, to treat HIV-1 infection in adults and children weighing at least 3 kg (about 4 weeks of age and older). It can also be paired with rilpivirine as a complete two-drug regimen in certain adults whose HIV is already well controlled. Tivicay is always used as part of a combination regimen, not on its own.
Is there a generic version of Tivicay?
No. As of now, there is no FDA-approved generic version of Tivicay (dolutegravir) available on the market, so Tivicay remains a brand-only medication.
What foods or supplements should be avoided while taking Tivicay?
Supplements and antacids containing calcium or iron can reduce how well your body absorbs dolutegravir if taken too close together. Ask your pharmacist about the correct spacing between these products and your Tivicay dose. Also tell your provider about all medications and supplements you take, since Tivicay has other important drug interactions, including with metformin and dofetilide.
What are the side effects of Tivicay?
The most commonly reported side effects of Tivicay are insomnia, fatigue, and headache. Tivicay's label also warns about possible liver problems (especially in people with hepatitis B or C), hypersensitivity reactions, immune reconstitution inflammatory syndrome, and a serious interaction with the heart medication dofetilide. Talk to your provider about any side effects you experience, and let your provider know about any other health conditions or medications.
How much does Tivicay cost, and is there a savings card?
Tivicay's price varies by pharmacy and location. Its manufacturer, ViiV Healthcare, offers its own savings card program, which is generally available to people with commercial insurance and has terms that vary. If you're uninsured, on Medicare, or can't use the manufacturer card, an Rx.com cash coupon may still help lower your price - enter your ZIP above to see today's price near you.
How much does Tivicay cost without insurance?
The price of Tivicay without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Tivicay?
Common side effects of Tivicay may include: Fever, chills, cough, sore throat, joint or muscle aches, unusual tiredness or weakness, Redness, pain, or swelling of or around your eye or eyelid, Blistering, peeling, or severe skin rash, Sores on your lips or mouth, Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Tivicay?
Generic versions may be available for Tivicay. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Tivicay on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Tivicay?
The cheapest pharmacy for Tivicay depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Tivicay near you.

Tivicay Coupons & Prices

Tivicay 50MG

Tivicay Tablet — prescription drug image
Prescription
Tivicay 50mg (5)
your area ·

If you're searching for a Tivicay coupon, here's what matters before you compare prices: Tivicay (dolutegravir) is a brand-name HIV integrase inhibitor with no generic version currently available, so lowering your cost comes down to which savings option you use, not a generic swap. ViiV Healthcare, the drug's manufacturer, offers its own savings card program, but it's generally limited to people with commercial insurance and terms vary. If you're uninsured, on Medicare, or your manufacturer card is declined at the pharmacy, an Rx.com cash coupon can still help - enter your ZIP above to see today's price at pharmacies near you.

What Is Tivicay (Dolutegravir)?

Tivicay is the brand name for dolutegravir (as dolutegravir sodium), an HIV integrase strand transfer inhibitor (INSTI). It's FDA-approved, in combination with other antiretroviral medications, to treat HIV-1 infection in adults and pediatric patients weighing at least 3 kg (roughly 4 weeks of age and older). Tivicay PD is an oral suspension tablet formulation for patients who need it. Per its label, dolutegravir can also be paired with rilpivirine as a complete two-drug switch regimen in certain adults whose HIV is already well controlled (virologically suppressed) on a stable regimen.

Tivicay is always taken together with other HIV medications as part of a combination regimen - it is not a cure for HIV and is not typically used off-label.

Tivicay Coupon: Manufacturer Savings Card vs. Rx.com Cash Price

ViiV Healthcare, the maker of Tivicay, runs its own savings card program through its patient site, but like most brand manufacturer cards, it's generally limited to people with commercial (private) insurance, and eligibility and terms can vary. If you have Medicare, are uninsured, or your ViiV card is declined at checkout, an Rx.com cash coupon can be used instead at participating pharmacies, since it doesn't depend on your insurance status.

Because Tivicay does not currently have a generic version on the market, there isn't a lower-cost generic swap to ask your pharmacist about - the coupon route is the main lever for lowering your out-of-pocket cost today. Enter your ZIP code above to see today's price at pharmacies near you.

Tivicay vs. Other HIV Treatment Options

Dolutegravir, the active ingredient in Tivicay, is also the backbone of several combination HIV pills, including Dovato (dolutegravir with lamivudine) and Triumeq (dolutegravir combined with abacavir and lamivudine) - both single-tablet regimens that pair dolutegravir with other antiretrovirals in one pill. Juluca combines dolutegravir with rilpivirine, similar to the two-drug switch option described on Tivicay's own label.

Other complete regimens, such as Biktarvy, are built around a different integrase inhibitor. Rilpivirine and lamivudine are also available as individual medications used in various HIV regimens. Any switch between HIV regimens should only be made with your provider's guidance - don't change your treatment on your own.

Tivicay Safety Information

Tivicay does not carry an FDA boxed warning, but its label lists several warnings and precautions worth knowing. Hypersensitivity reactions - rash along with constitutional symptoms (like fever or fatigue) and sometimes organ dysfunction, including liver injury - have been reported with Tivicay. Treatment should be stopped right away if signs of a hypersensitivity reaction develop, since delaying can lead to a life-threatening reaction. Tivicay can also cause liver problems (hepatotoxicity), particularly in patients also living with hepatitis B or C, and patients should not stop hepatitis B treatment abruptly since doing so can trigger liver-related flares.

Tivicay must not be taken with dofetilide, a heart-rhythm medication, because the combination can raise dofetilide to dangerous, potentially fatal levels. Because Tivicay is an integrase inhibitor, people who have taken other INSTI medications before may have fewer treatment options due to drug resistance.

Supplements and antacids containing calcium or iron can reduce how much dolutegravir your body absorbs, so these typically need to be spaced apart from your Tivicay dose - ask your pharmacist for guidance. Dolutegravir can also raise levels of metformin, so your provider may need to adjust your metformin dose if you take both. The most commonly reported side effects are insomnia, fatigue, and headache; immune reconstitution inflammatory syndrome has also been reported as the immune system recovers. This is general information, not medical advice - talk with your provider or pharmacist about your specific situation.

Sources & accuracy

This Tivicay information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Tivicay on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.