¿Qué es Adakveo?

Adakveo (crizanlizumab-tmca) es un medicamento de anticuerpos monoclonales desarrollado para reducir la frecuencia de crisis vaso-oclusivas en individuos con enfermedad de células falciformes de 16 años en adelante. Funciona bloqueando la P-selectina, una molécula de adhesión celular involucrada en la inflamación de los vasos sanguíneos y las obstrucciones. Administrado a través de infusión intravenosa, Adakveo ayuda a prevenir los episodios dolorosos y las complicaciones asociadas con estas crisis.

Side Effects

• Fever, chills, cough, sore throat, dizziness, diarrhea, nausea, vomiting, stomach pain, sweating, trouble breathing, tiredness
• Chest pain or discomfort, confusion, headache, numbness or tingling in the face, arms, or legs, trouble walking or speaking
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Warnings

• Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
• Tell your doctor if you are pregnant or breastfeeding.
• Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
• This medicine may cause infusion-related reactions, which can be life-threatening and require medical attention.