¿Qué es Teriflunomide?

Teriflunomida es un fármaco inmunomodulador utilizado principalmente para tratar formas recurrentes de esclerosis múltiple (EM). Actúa inhibiendo la enzima dihidroorotato deshidrogenasa, reduciendo la proliferación de linfocitos T y B activados, que se cree contribuyen al ataque autoinmune contra la mielina.

Side Effects

• Swollen, painful, or tender lymph glands in your neck, armpit, or groin
• Fast, slow, or pounding heartbeat
• Unusual bleeding, bruising, or weakness

Warnings

• This medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting treatment. Use an effective form of birth control to prevent pregnancy.
• Teriflunomide may stay in your blood for up to 2 years after you stop using it. Your doctor can give you medicine to remove it from your body faster, if needed. Talk to your doctor if you have questions or concerns about this.
• Do not breastfeed during treatment with this medicine
• Tell your doctor if you have kidney disease, liver disease, bone marrow problems, diabetes, high blood pressure, lung disease, nerve problems, any type of infection, or a history of tuberculosis.
• This medicine may cause the following problems:Liver problemsLung problemsIncreased risk of cancerPeripheral neuropathySerious skin reactions (including Stevens-Johnson syndrome, toxic epidermal necrolysis)Drug reaction with eosinophilia and systemic symptoms (DRESS), which may affect multiple organs, including liver, kidneys, or heart