Aluminum Chloride Anhydrous
Aluminum Chloride Anhydrous
What is Aluminum Chloride Anhydrous?
Aluminum Chloride Anhydrous is a powerful Lewis acid used primarily in pharmaceutical and cosmetic applications, particularly in antiperspirant products. Its chemical efficacy stems from its ability to react with water to form hydrochloric acid and aluminum hydroxide, which can modulate sweat production by altering sweat gland ducts. In medicinal formulations, it is utilized for its astringent and antiseptic properties, especially in managing hyperhidrosis.
Side Effects
- Skin irritation and dryness
- Burning sensation or stinging at the application site
Warnings
- Avoid contact with eyes and mucous membranes
- Do not apply to broken or irritated skin
Prescription savings · · · ·
What is Aluminum Chloride Anhydrous ?
Aluminum Chloride Anhydrous is a powerful Lewis acid used primarily in pharmaceutical and cosmetic applications, particularly in antiperspirant products. Its chemical efficacy stems from its ability to react with water to form hydrochloric acid and aluminum hydroxide, which can modulate sweat production by altering sweat gland ducts. In medicinal formulations, it is utilized for its astringent and antiseptic properties, especially in managing hyperhidrosis.
- Skin irritation and dryness
- Burning sensation or stinging at the application site
- Avoid contact with eyes and mucous membranes
- Do not apply to broken or irritated skin
Aluminum Chloride Anhydrous Coupons & Prices
Aluminum Chloride Anhydrous
An aluminum chloride anhydrous coupon from Rx.com can lower what you pay for prescription-strength aluminum chloride hexahydrate topical solution, the anhydrous-ethyl-alcohol antiperspirant used for hyperhidrosis (excessive sweating) of the underarms, palms, and soles. It is sold under brand names such as Drysol, Xerac AC, and Hypercare, and a generic version of the solution is available. Cash prices for the same bottle can differ a lot from one pharmacy to the next, so it pays to compare. Rx.com checks prices across 60,000+ pharmacies. Enter your ZIP above to see today's price near you, then show the coupon at the counter.
What is aluminum chloride anhydrous and how does it work?
Aluminum chloride hexahydrate in anhydrous ethyl alcohol is a topical antiperspirant and astringent (a metal salt) used for hyperhidrosis, or excessive sweating. It is applied to the skin, where it works at the sweat-duct openings to reduce how much sweat reaches the surface. The prescribing information for the 20% prescription solution describes it as a topical treatment for severe, recalcitrant hyperhidrosis, and says it is suited to sweating of the axillae (underarms), palms, and soles. Dermatology guidelines and clinical literature also commonly describe topical aluminum chloride as an early or first-line option for primary focal hyperhidrosis, but that framing comes from guidelines rather than the FDA-approved labeling.
Aluminum chloride solutions are marketed at more than one strength: the prescription Drysol solution is dispensed as 20% aluminum chloride hexahydrate, and Xerac AC (Person & Covey) is 6.25%. The usual approach is to apply the solution to clean, completely dry skin at bedtime and wash it off after 6 to 8 hours, repeating nightly until sweating is controlled, then dropping back to once or twice weekly for maintenance. Your prescriber or pharmacist will tell you what is right for you; this page is information, not medical advice.
What aluminum chloride costs without insurance, and why comparing matters
A generic version of aluminum chloride hexahydrate solution is available, and many people buy it with cash rather than run it through insurance. That does not mean every pharmacy charges the same thing. Cash prices for the identical bottle and strength can vary widely between one chain and the independent pharmacy down the street, which is exactly why comparing before you fill is worth the minute it takes.
Rx.com compares prices across more than 60,000 pharmacies and shows you a coupon you can use at the counter without insurance. Enter your ZIP above to see today's price near you. Also worth knowing: whether a given aluminum chloride antiperspirant is prescription or over the counter depends on the specific product and its concentration, not on the alcohol base. Higher-strength solutions such as the 20% Drysol solution are dispensed by prescription, while a number of aluminum chloride antiperspirants, including lower-strength products and brands like Certain Dri and Duradry, are sold over the counter. Ask your clinician or pharmacist which one fits your situation.
Brands and alternatives for excessive sweating
Aluminum chloride hexahydrate solutions are sold under brand names including Drysol, Xerac AC, and Hypercare. Drysol is marketed in more than one strength, and the prescription Drysol solution is 20%; Xerac AC is 6.25%. Because these products share the same active ingredient at different strengths, the choice usually comes down to how strong a product your skin tolerates and where on the body you are treating, so check the strength on the bottle you are actually given.
If a topical antiperspirant is not enough, clinicians may consider other options, including the topical anticholinergic wipe Qbrexza or oral anticholinergics such as glycopyrrolate and oxybutynin. These work differently and have their own side effects, so talk with your provider about which path makes sense before switching.
Safety, side effects, and how to use it comfortably
Aluminum chloride solution has no boxed warning. It is for external use only and should not be swallowed. Do not apply it to broken, irritated, or recently shaved skin, or right after bathing. Keep it away from the eyes and mucous membranes. It is not for people allergic to aluminum salts.
The most common effects are burning, stinging, itching, prickling, and skin irritation where you apply it. Irritation can usually be reduced by applying to completely dry skin at bedtime and washing it off after 6 to 8 hours. Because the base is anhydrous alcohol, the solution is flammable, so keep it away from flame. It may be harmful to fabrics such as cotton, and it can damage certain metals. Stop using it and contact a clinician if severe irritation or a rash develops. This is a summary, not medical advice, so read the label that comes with your bottle and ask your pharmacist or prescriber about your own situation.
This Aluminum Chloride Anhydrous information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Aluminum Chloride Anhydrous on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.